Influence of two different perfusion systems on inflammatory
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LAD, = left anterior descending coronary artery. PTCA, = percutaneous transluminal coronary angioplasty Carmeda BioActive Surface (CBAS) (Medtronic Inc,. Minneapolis, Minn) involves deposition of a polymer coating, polyethylenimine, onto various types of sur-. heparin (CBAS Carmeda, Medtronic), closed venous res- ervoir, hollow-fiber oxygenator (Maxima Carmeda,.
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The general principle of the CARMEDA ® BioActive Surface technology is to attach functionally active heparin to the blood contacting surfaces of medical devices. Heparin is covalently bound to the surface by end-point attachment. This proprietary coupling technique is the key to thromboresistance and long-term stability. CBAS stands for Carmeda BioActive Surface (also Cost-Benefit Analyses and 82 more) Of the various heparin-based technologies, the CARMEDA ® BioActive Surface (CBAS ® Heparin Surface; Carmeda AB, Upplands Väsby, Sweden), has the most extensive publication history describing both basic biochemical mechanisms and clinical applications. The CARMEDA ® BioActive Surface is a clinically proven and lasting thromboresistant heparin coating that actively prevents platelet adhesion and thrombus formation on medical device surfaces.
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heparin (CBAS Carmeda, Medtronic), closed venous res- ervoir, hollow-fiber oxygenator (Maxima Carmeda,. Medtronic), cardiotomy reservoir (Intersept, Carmeda AB develops, produces, and markets biocompatible coatings for medical devices. The Company offers a hemocompatible surface coating, which is end-point attachment mechanism (CARMEDA® BioActive Surface(CBAS® Surface)) which serves to anchor heparin molecules to the luminal surface while still Carmeda AB, a Swedish company, invented the CBAS Heparin Surface, an end- point attached heparin technology used on the GORE® ACUSEAL Vascular Jan 31, 2018 CBAS Heparin Surface CBAS is a trademark of Carmeda AB, a wholly owned subsidiary of W.L. Gore & Associates, Inc. © 2017 W. L. & Gore Carmeda is a manufacturer of hemocompatible surface coating for medical devices.
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Almost 700 global scientific reports have been published on the chemistry, biological properties, safety and clinical performance of the CARMEDA ® BioActive Surface technology.
Carmeda trademarks may be used only in conjunction with the sale of products in which Carmeda technologies are incoporated or with the express permission
Carmeda is a medical coating company, certified to ISO13485. We develop and manufacture biocompatible coating technologies. Carmeda’s mission is to save and improve the quality of life for people by providing high-performance coatings
Gore’s CBAS Heparin Surface, the proven heparin bonding technology for lasting thromboresistance, is used in many of our interventional and vascular surgery products. End-point covalent bonding keeps heparin anchored to the device, while the bioactive site remains free to interact with the blood to help prevent clotting. 2017-03-01 · CARMEDA ® BioActive Surface (CBAS ® Heparin Surface) This heparin bonding technology was developed by Carmeda AB, a wholly owned subsidiary of W.L. Gore & Associates, Inc. The technology has been used in a variety of applications including CPB equipment, hemodialysis catheters, ventricular assist devices, vascular stents, stent grafts, and vascular grafts. Evaluation of Carmeda bioactive surface (CBAS), Duraflo II and a novel nonspecific protease-modified surface using a new in vitro model simulating cardiopulmonary bypass. Yii M(1), Gourlay T, Fleming J, Matata B, Taylor KM. Author information: (1)Department of Cardiothoracic Surgery, Hammersmith Hospital, London.
Skip to main content and n = 57), the presence of the CARMEDA® BioActive Surface was not found to contribute to an increased rate of HIT antibody formation or persistence of the antibodies over time 17,18 Administration of systemic heparin confounds interpretation of the cause of HIT events. 3 Disposable and implantable medical devices, namely, vascular grafts, stent grafts, vascular stents; [ cardiopulmonary bypass circuits, centrifugal pump circuits, artificial hearts, ventricular assist devices, namely, external or implantable devices to replace or support the function of the heart; medical tubing for use in drainage, transfusion, and administering drugs, and filters and cannulae Because of its extensive publication history, there is emphasis on the Carmeda® Bioactive Surface (CBAS® Heparin Surface), a widely used commercialized technology for the covalent bonding of clinical publications related to the CBAS® Surface. Who is Carmeda AB? Carmeda AB, a Swedish company, invented the end-point heparin bonding technology used on the GORE ® PROPATEN Vascular Graft and other medical devices.
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End-point attached (EPA) heparin, using the proprietary Carmeda Bioactive Surface (CBAS Surface), was compared with other methods of covalent heparin bonding that typically yield multiple covalent linkages (using reductive amination of periodate oxidized native heparin or EDC coupling of native heparin).
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The following features and benefits of the CARMEDA ® BioActive Surface have been shown in published clinical studies and scientific papers: What is the abbreviation for Carmeda BioActive Surface? What does CBAS stand for? CBAS abbreviation stands for Carmeda BioActive Surface. The available experimental evidence and emerging clinical results point to significant clinical benefits of the stable CBAS Heparin Surface immobilization on the GORE PROPATEN Vascular Graft. The CBAS Heparin Surface provides important beneficial effects, which include sustained thromboresistance and reduced platelet attachment. CBAS is a trademark of Carmeda AB, a wholly owned subsidiary of W. L. Gore & Associates, Inc. Featured Gore Products with CBAS Heparin Surface GORE ® PROPATEN ® Vascular Graft 50% reduction in the risk of graft occlusion compared to standard ePTFE in Critical Limb Ischemia (CLI) patients 1 Watch CBS television online.